Patients with RH were randomized in a 1 1 ratio to either 1 a catheter based RDN plus optimal antihypertensive treatment group unchanged after randomization, thus including spironolactone only in rare cases where patients were already using the drug before entering the study or to 2 an intensified pharmacological treatment group PHAR, including spironolactone if tolerated and not contraindicated levitra bayer espana
